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Disease
Activity and Disability Assessment Instruments
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Complete
agreement does not exist with regard to the specific instruments that should
be used to measure disease activity; however, a questionnaire directed at
specialists in the field of AS indicates that many experts prefer the Bath AS
Disease Activity Index (BASDAI) and/or the Bath AS Functional Index (BASFI).1,2
The ASsessment in Ankylosing Spondylitis Improvement Criteria (ASAS-IC), a
composite of four domains, have also been evaluated recently and were
concluded to be strict in defining response and highly specific as well.3
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1. Braun J,
Sieper J. Building consensus on nomenclature and disease classification for
ankylosing spondylitis: results and discussion of a questionnaire prepared
for the International Workshop on New Treatment Strategies in Ankylosing Spondylitis, Berlin, Germany,
January 18-19, 2002. Ann Rheum Dis. 2002;61(suppl III):iii61-iii67.
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2. Braun J, Pham
T, Sieper J, et al for the ASAS Working Group. International ASAS consensus
statement for the use of anti-tumor necrosis factor agents in patients with
ankylosing spondylitis. Ann Rheum Dis. 2003;62:817-824.
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3. van Tubergen
A, van der Heijde D, Anderson J, et al for the ASAS Working Group. Comparison
of statistically derived ASAS
improvement criteria for ankylosing spondylitis with clinically relevant
improvement according to an expert panel. Ann Rheum Dis.
2003;62:215-221.
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